Scientific publications


Hoekman J, Lambers Heerspink HJ, Viberti G, Green D, Mann JFE, de Zeeuw D (2014) Predictors of congestive heart failure after treatment with an endothelin receptor antagonist: a post-hoc analysis of the Avosentan on time to doubling of Serum Creatinine, ENd stage renal disease or Death (ASCEND) trial. Clinical Journal of the Association of Nephrology, 9 (3): 490-498. [ABSTRACT]
Smink PA, Hoekman J, Grobbee DE, Eijkemans EC, Parving H-H, Ibsen H, Lindholm L, Wachtell K, de Zeeuw D, Lambers Heerspink HJ (2013) A prediction of the renal and cardiovascular efficacy of aliskiren in ALTITUDE using short term changes in risk markers. European Journal of Preventive Cardiology, 21 (4): 434-444.
Schievink B, Heerspink HJL, Leufkens H, de Zeeuw D, Hoekman J (2014) The use of surrogate endpoints in regulating medicines for cardio-renal disease: opinions of stakeholders. PLoS ONE, 9(9), 108722.
Rafols I, Hopkins M, Hoekman J, Siepel J, O’hare A, Perianes-Rodriguez A, Nightingale P (2014) Big Pharma, Little Science? A bibliometric analysis on Big Pharma’s R&D decline. Technological Forecasting and Social Change, 81: 22-38.
Smink PA, Miao Y, Eijkemans MJC, Bakker SJL, Raz I, Parving HH, Hoekman J, Grobbee DE, De Zeeuw D, Heerspink, HL (2014) The importance of short-term off-target effects in estimating the long-term renal and cardiovascular protection of angiotensin receptor blockers. Clinical Pharmacology & Therapeutics, 95(2), 208-215.


Hoekman J, Scherngell T, Frenken K, Tijssen RJW (2013) Acquistion of European research funds and its effect on scientific publications. Journal of Economic Geography, 13: 23-51.


Hoekman J, Frenken K, de Zeeuw D, Lambers Heerspink HJ (2012) The geographical distribution of leadership in globalized clinical trials. PLoS ONE, 7(10), e45984.


Vinciguerra S, Frenken K, Hoekman J, van Oort FG (2011) European infrastructure networks and regional innovation in science-based industries. Economics of Innovation and New Technology, 20(5): 517-537.


Hoekman J, Frenken K, Tijssen RJW (2010) Research collaboration at a distance: changing spatial patterns of scientific collaboration in Europe. Research Policy, 39(5): 662-673.


Hoekman J, Frenken K, van Oort, FG (2009) The geography of collaborative knowledge production in Europe. The Annals of Regional Science, 43(3): 721-738.
Frenken K, Hardeman S, Hoekman J (2009) Spatial scientometrics: towards a cumulative research program. Journal of Informetrics, 3(3): 222-232.


Frenken K, Hoekman J (2006) Convergence in an enlarged Europe: the role of network cities. Journal of Economic and Social Geography (TESG), 97(3): 321-326.